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A review of dialysis profiling
Author(s) -
PARSONS Darren S,
HARRIS David CH
Publication year - 1998
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/j.1440-1797.1998.tb00364.x
Subject(s) - medicine , ultrafiltration (renal) , profiling (computer programming) , dialysis , bicarbonate , potassium , intensive care medicine , hydrostatic pressure , chromatography , chemistry , computer science , thermodynamics , operating system , physics , organic chemistry
SUMMARY: The movement of water or other chemical species across the dialysis membrane can be controlled by altering the concentration of dialysate constituents or the hydrostatic pressure within the dialysis compartment. So‐called dialysis profiling is most commonly applied to dialysate sodium concentration or ultrafiltration rate in an attempt to reduce the frequency of intradialytic hypotension or ‘dysequilibrium’ symptoms. Such an approach can be applied to other dialysate constituents, for example potassium and bicarbonate. Increasingly complex dialysis machines allow these profiles to be preprogrammed according to several patterns. In recent years the use of on‐line monitoring systems has allowed a further refinement such that these profiles can be adjusted during dialysis. Despite the theoretical advantages of profiling, the benefits of such techniques have not been consistently demonstrated. This review examines profiling of sodium, ultrafiltration, potassium and bicarbonate, and the evidence for their use.