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Risk factors and outcome of hypertension in living related renal transplant recipients
Author(s) -
SUD K,
RAO M,
JACOB CK,
SHASTRY JCM
Publication year - 1995
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/j.1440-1797.1995.tb00052.x
Subject(s) - medicine , immunosuppression , transplantation , risk factor , renal transplant , kidney transplantation , renal function , surgery
Summary: Impaired allograft function is an important cause of hypertension in cadaveric renal transplant recipients. the risk factors for post‐tranplant hypertension in living related transplant recipients with inherent good graft functions are likely to be different and have not been studied. In addition, controversy surrounds any independent effect hypertension might have on renal allograft functions. Four hundred and seventy three living related renal allograft recipients were retrospectively analysed to study the risk factors for development of post‐transplant hypertension and its effect on graft outcome. Prevalence of hypertension was 76.1%. the presence of pre‐transplantation hypertension was the most important independent risk factor for development of hypertension after transplantation. This suggests an important role of retained native diseased kidneys as a cause of hypertension. Other risk factors included: cyclosporin A immunosuppression, patient age less than 40 years and the presence of renal insufficiency at last follow up. Hypertension did not have any effect on patient or graft survival during the mean follow‐up period of 20.1 ± 13.7 months; however, it was associated with an independent risk for the presence of renal insufficiency in the post‐transplant period.