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Pigmented pleomorphic xanthoastrocytoma: A rare variant and literature review
Author(s) -
Xiong Ji,
Chu ShuGuang,
Mao Ying,
Wang Yin
Publication year - 2011
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/j.1440-1789.2010.01132.x
Subject(s) - pleomorphic xanthoastrocytoma , pathological , pathology , magnetic resonance imaging , immunohistochemistry , medicine , ganglioglioma , temporal lobe , anatomy , radiology , glioblastoma , astrocytoma , epilepsy , cancer research , psychiatry
A 16‐year‐old male teenager presented with seizure and loss of consciousness for 20 min. Magnetic resonance imaging demonstrated a mass occupying the right medial temporal lobe. Histological examination revealed a non‐pigmented area with spindle‐shaped and large xanthomatous pleomorphic cells and a pigmented region with pigmented neoplastic cells with fascicular arrangement. Immunohistochemical studies showed the tumor was positive for GFAP and low index of Ki‐67. Considering the patient's history, clinical data and pathological findings, we rendered a rare variant named pigmented pleomorphic xanthoastrocytoma.