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Giant cell angiitis of the central nervous system with atypical presentation
Author(s) -
Ciappetta Pasqualino,
D'Urso Pietro Ivo,
Colamaria Antonio,
Lauta Enrico,
Cimmino Antonia,
D'Urso Oscar Fernando,
Rossi Roberta,
Resta Leonardo,
Ingravallo Giuseppe
Publication year - 2010
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/j.1440-1789.2009.01073.x
Subject(s) - medicine , pathology , vasculitis , giant cell , lesion , presentation (obstetrics) , central nervous system , stroke (engine) , disease , intracerebral hemorrhage , giant cell arteritis , radiology , surgery , subarachnoid hemorrhage , mechanical engineering , engineering
Giant cell angiitis of the CNS is an uncommon form of vasculitis. Neurological manifestations, both of the peripheral and CNS, are common. The most frequent manifestations are visual loss and stroke. Hemorrhagic onset is uncommon. Most cases have a fatal outcome and a tissue diagnosis is rarely established in life. We describe an unusual case of giant cell angiitis beginning as a hemorrhagic tumoral‐like lesion. The results of the histological and ultrastructural analysis have also been reported. Our case illustrates that giant cell angiitis should be considered as a cause of intracerebral hemorrhage, particularly when associated with a relapsing and remitting disease of the CNS.