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Spherical amyloid deposition in a prolactin‐producing pituitary adenoma
Author(s) -
Gul Sanser,
Bahadir Burak,
Dusak Abdurrahim,
Kalayci Murat,
Edebali Nurullah,
Acikgoz Bektas
Publication year - 2009
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/j.1440-1789.2008.00922.x
Subject(s) - prolactin , pituitary adenoma , medicine , adenoma , pathology , pituitary gland , magnetic resonance imaging , hormone , radiology
A 41‐year‐old man presented with headache, right‐sided ophthalmic pain and visual deficit. His neurological examination was normal except for bitemporal hemianopsia and right lower quadranopsia. MRI demonstrated a mass arising from the pituitary gland. Hormonal analysis revealed an elevated prolactin level of 4700 ng/mL (normal 4.04–15.2 ng/mL). MRI revealed hypointense signal on T2‐weighted images. Moreover, we also concluded that foci with no intravenous contrast enhancement represent the amyloid deposits. The patient underwent trans‐sphenoidal resection of the pituitary adenoma. Histological examination revealed an adenoma with spheroid amyloid deposits adjacent to prolactin‐staining adenoma cells. The patient recovered from the surgery without complications.