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Pineal germinoma associated with multiple congenital melanocytic nevi: A unique presentation
Author(s) -
Aker Fügen V.,
Berkman Zafer M.,
Aydıngöz İkbal,
Hakan Tayfun,
Toksoy Güven
Publication year - 2005
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/j.1440-1789.2005.00617.x
Subject(s) - germinoma , germ cell tumors , congenital melanocytic nevus , pathology , medicine , pathological , germ cell , occipital region , nevus , melanoma , anatomy , biology , radiology , radiation therapy , cancer research , chemotherapy , biochemistry , gene
Intracranial germ cell tumors are rarely seen and typically localize in the pineal or suprasellar region. The largest category of germ cell tumors is the germinoma. There have been reported associations of malignant tumors and chromosomal abnormalities in germ cell tumors. In this study, we present a 22‐year‐old man with multiple congenital melanocytic nevi in association with pineal tumor. Congenital melanocytic lesions greater than 2 cm were counted to be 54 in number, and those smaller than 1 cm in diameter were found to be 25 in number. The pathological diagnosis of the pineal tumors was germinoma, and the lesions located in the occipital region and trunk were compound congenital nevi. To our knowledge, a relationship between multiple congenital melanocytic nevi and germ cell tumors has not been reported before. The connection between them remains to be clarified.