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Angioma of the choroid plexus: Personal experience of 42 cases and a review of the literature
Author(s) -
Shuangshoti Shanop,
Shuangshoti Samruay
Publication year - 1997
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/j.1440-1789.1997.tb00060.x
Subject(s) - choroid plexus , medicine , angioma , lesion , choroid , ventricle , intraventricular hemorrhage , plexus , fourth ventricle , surgery , radiology , central nervous system , vascular disease , retina , gestational age , psychology , pregnancy , biology , genetics , neuroscience
Only 127 cases have been reported of choroidal angiomas, including the 42 examples cited in the present paper. The mean age of the 42 subjects examined in the present series was 15 years and the median was 1 month. The lateral ventricle was the most common location. Bilateral angiomas comprised 40% of lesions in the lateral ventricle, which is strikingly more common than in previous reports (8%). Most patients presented with signs and symptoms of intraventricular or subarachnoid hemorrhage. The lesion, however, was found accidentally in 15 cases (36%), particularly in the perinatal period. Associated developmental malformations were observed in 25 instances (59%), which often involved the cardiovascular system. The median age of 30 years of patients with choroid plexus angioma in the literature is significantly ( P < 0.005) higher than that in the present study. Of 85 cases of choroidal angioma reported in the literature, only three cases (4%) were encountered accidentally. It is suggested that careful examination of the choroid plexus will increase the diagnosis of choroidal angiomas and that hemangiomas should be searched for in the choriod plexus in cases of intraventricular hemorrhage as well as in instances of developmental malformations, particularly those affecting the cardiovascular system.