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Molecular pathology of Alzheimer's disease
Author(s) -
Yamazaki Tsuneo,
Ihara Yasuo
Publication year - 1997
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/j.1440-1789.1997.tb00051.x
Subject(s) - disease , molecular pathology , alzheimer's disease , medicine , pathology , biology , bioinformatics , gene , genetics
Recent molecular and cellular approaches to the nature of Alzheimer's disease (AD) have revealed that the disease has a heterogenous genetic background. Thus, AD is not a disease but a syndrome. In the present article we review the significance of the causative and susceptibility genes of AD identified to date and discuss future perspectives of AD research.