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Correlation between glioblastoma cell infiltration and T2 prolongation on magnetic resonance imaging
Author(s) -
Tamura Masaru,
Zama Akira,
Kurihara Hideyuki,
Ono Nobuo,
Kano Tomoaki,
Imai Hideaki,
Ishiuchi Shougo,
Nakazato Yoichi
Publication year - 1997
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/j.1440-1789.1997.tb00036.x
Subject(s) - infiltration (hvac) , magnetic resonance imaging , glioblastoma , medicine , edema , pathology , biopsy , gadolinium , nuclear medicine , radiology , chemistry , materials science , cancer research , organic chemistry , composite material
Tumor cell infiltration around the tumor tissue in glioblastoma was investigated in 13 patients with glioblastoma who underwent gross total tumor removal. Thirty‐four glioblastoma cases were operated on between January 1988 and December 1995. T1‐weighted magnetic resonance imaging (MRI) with gadolinium enhancement was used to measure tumor size, and T2‐weighted MRI to detect perilesional edema. Biopsy samples of surrounding tissue taken after tumor removal were histologically examined. Small tumors (< 3 cm diameter) and moderatesized tumors with mild perilesional edema had no or few infiltrating tumor cells in the surrounding tissue. In contrast, large tumors (> 6 cm diameter) with moderate or high perilesional edema had intensive tumor cell infiltration.