Premium
Recurrent intussusception in infants
Author(s) -
Justice Frances A,
Nguyen Liem T,
Tran Son N,
Kirkwood Carl D,
Thi Ngo Thi,
Carlin John B,
Bines Julie E
Publication year - 2011
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2011.02029.x
Subject(s) - medicine , pediatrics , natural history , intussusception (medical disorder) , medical record , retrospective cohort study , clinical endpoint , presentation (obstetrics) , prospective cohort study , pathological , surgery , randomized controlled trial
Aim: Clinical features to identify infants at increased risk of recurrence after a primary episode of intussusception (IS) are poorly defined. Methods: Prospective study of the clinical presentation, treatment and outcome in infants <2 years presenting with acute IS to the National Hospital of Pediatrics, Hanoi, over a 14‐month period (1 November 2002 to 31 December 2003). A retrospective review of medical records was performed to verify complete patient ascertainment. Results: Five hundred ninety‐eight children were recruited, including 513 (86%) with a primary episode only and 53 (9%) with ≥1 recurrent episodes. Another 32 (5%) infants presented with recurrent IS, but the primary episode of IS occurred outside the study period. Estimated recurrence risk at 6 months following a primary episode was 14%. A pathological lead point was rare in primary ( n = 1) and recurrent IS ( n = 1). Most infants were successfully treated with enema reduction. Conclusions: This study describes the natural history of recurrent IS in infants and may assist in interpreting data from post‐marketing surveillance following introduction of rotavirus vaccines.