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Long‐standing fever and Angelman syndrome: Report of two cases
Author(s) -
Yiş Uluç,
Giray Özlem,
Kurul Semra H,
Bora Elçin,
Ulgenalp Ayfer,
Erçal Derya,
Dirik Eray
Publication year - 2008
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2008.01302.x
Subject(s) - medicine , angelman syndrome , pediatrics , high fever , girl , surgery , developmental psychology , biochemistry , chemistry , gene , psychology
An 8‐month‐old girl and a 20‐month‐old boy who presented with motor and developmental delay and long‐standing fever are presented. The patients were diagnosed as Angelman syndrome with fluorescence in situ hybridization (FISH) analysis. Despite extensive clinical and laboratory examinations, no inflammatory or infectious origin for the fever was found. It was considered that the long‐standing fever observed in these cases was due to hypothalamic dysfunction for thermoregulation.