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Isolated thrombocytopenia in children: Thinking beyond idiopathic thrombocytopenic purpura and Leukaemia
Author(s) -
Kottayam Radhakrishnan,
Rozenberg Gillian,
Brighton Tim,
Cohn Richard J
Publication year - 2007
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2007.01240.x
Subject(s) - medicine , thrombocytopenic purpura , bernard–soulier syndrome , presentation (obstetrics) , pediatrics , purpura (gastropod) , dermatology , immunology , platelet , surgery , ecology , biology
The commonest cause of isolated thrombocytopenia in an otherwise well child is idiopathic thrombocytopenic purpura (ITP). The inherited thrombocytopenias such as Bernard–Soulier syndrome are rare but often misdiagnosed as ITP owing to a similar clinical presentation. We describe a child with Bernard–Soulier syndrome who presented with isolated thrombocytopenia, mimicking ITP. Features which help to differentiate these two conditions are discussed with a brief literature review.