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Early intervention for the ocular and neurodevelopmental sequelae of Fetal Valproate Syndrome
Author(s) -
Carrim Zia I,
McKay Lorna,
Sidiki Sikander S,
Lavy Timothy E
Publication year - 2007
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2007.01176.x
Subject(s) - medicine , intervention (counseling) , pediatrics , craniofacial , neural tube , congenital malformations , fetus , neurodevelopmental disorder , pregnancy , psychiatry , autism , embryo , genetics , biology , microbiology and biotechnology
The established teratogenicity of antiepileptic drugs raises important issues in women of child‐bearing age. While the association between neural tube defects and antiepileptic drugs is well recognised, other congenital malformations are known to occur. We report two siblings with characteristic craniofacial features of Fetal Valproate Syndrome who also had associated ocular and neurodevelopmental problems which would benefit from early recognition and intervention.