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Twin pregnancy with a coexisting hydatiform mole and liveborn infant: Complicated by maternal hyperthyroidism and neonatal hypothyroidism
Author(s) -
True Deanna K,
Thomsett Michael,
Liley Helen,
Chitturi Sridhar,
Cincotta Robert,
Morton Adam,
Cotterill Andrew
Publication year - 2007
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2007.01145.x
Subject(s) - medicine , twin pregnancy , obstetrics , pregnancy , fetus , genetics , biology
A twin pregnancy with a coexisting complete hydatiform mole and a healthy fetus is rare. Associated with this condition are potentially serious maternal and fetal complications. We describe a case of a woman, 23/40 pregnant, who was diagnosed with a twin pregnancy complicated by a hydatiform mole, vaginal bleeding, hyperthyroidism and preterm labour at 26/40. Her hyperthyroidism was successfully treated with propylthiouracil. The preterm labour resulted in the livebirth of a healthy male infant. The baby developed biochemical hypothyroidism post‐natally. The baby’s thyroid function tests were unexpected, revealing a low T4 and a low‐normal thyroid stimulating hormone. This is the first case reported in the literature to describe an infant’s clinical and biochemical thyroid status after gestational trophoblastic disease complicated by hyperthyroidism.