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Botulinum neurotoxin A: An unusual systemic effect
Author(s) -
Howell Katherine,
Selber Paulo,
Graham H Kerr,
Reddihough Dinah
Publication year - 2007
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2007.01122.x
Subject(s) - medicine , botulinum neurotoxin , cerebral palsy , neurotoxin , pseudobulbar palsy , anesthesia , pediatrics , surgery , physical medicine and rehabilitation , toxin , biochemistry , chemistry
Systemic effects from Botulinum neurotoxin A are uncommon but can have serious consequences. We report the case of a boy with severe cerebral palsy who developed deterioration in respiratory and oromotor function following repeated injections of Botulinum neurotoxin A. Caution is needed in using this treatment in children with severe cerebral palsy and pseudobulbar palsy.