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Successful treatment of cutaneous and subcutaneous zygomycosis in an immunosuppressed patient with aplastic anaemia
Author(s) -
Chan Yumin,
Goldwater Paul,
Saxon Ben
Publication year - 2007
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2007.01010.x
Subject(s) - zygomycosis , medicine , neutropenia , surgery , posaconazole , aplastic anemia , mucormycosis , dermatology , amphotericin b , antifungal , chemotherapy , bone marrow
Zygomycosis in patients with persistent neutropenia had been associated with poor outcomes despite aggressive surgical and antifungal therapy. We describe the case of a 10‐year‐old girl with aplastic anaemia and persistent neutropenia who developed cutaneous and subcutaneous zygomycosis of her right thigh that was successfully treated with extensive surgical debridement, intravenous liposomal amphotericin B, later changed to oral posaconazole for long‐term suppressive therapy and granulocyte colony stimulating factor.