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Broad‐range polymerase chain reaction for the diagnosis of Bartonella henselae endocarditis
Author(s) -
Walls Tony,
Moshal Karyn,
Trounce John,
Hartley John,
Harris Kathryn,
Davies Graham
Publication year - 2006
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2006.00900.x
Subject(s) - medicine , bartonella , endocarditis , bartonella henselae , polymerase chain reaction , cat scratch disease , pathology , disease , virology , immunology , gene , biochemistry , serology , antibody , chemistry
We present a case of subacute bacterial endocarditis in a 10‐year‐old girl with Di‐George syndrome, congenital heart disease, and mild immunodeficiency. She was afebrile at initial presentation but was found to have massive splenomegaly, and signs of congestive heart failure. No causative organism could be identified on routine blood and tissue cultures. A detailed clinical history revealed a history that she had been scratched by a cat and developed intermittant fevers over 3 months. Bartonella henselae was identified by broad‐range 16S r‐DNA polymerase chain reaction on valvular tissue specimens.