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Successful treatment of cytomegalovirus‐associated haemophagocytic syndrome following paediatric orthotopic liver transplantation
Author(s) -
Hardikar Winita,
Pang Ken,
AlHebbi Homoud,
Curtis Nigel,
Couper Richard
Publication year - 2006
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2006.00879.x
Subject(s) - medicine , cytomegalovirus , cytomegalovirus infection , liver transplantation , cytomegalovirus infections , transplantation , pediatrics , intensive care medicine , immunology , human cytomegalovirus , herpesviridae , viral disease , virus
Haemophagocytic syndrome (HPS) following orthotopic liver transplantation is a rare event which is often fatal. We report here a case of HPS in association with cytomegalovirus (CMV) reactivation. The patient was treated with a combination of antiviral agents, immunomodulatory and supportive therapy which resulted in suppression of CMV infection and resolution of the haemophagocytosis.