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Combination pharmacotherapy for severe neonatal pulmonary hypertension
Author(s) -
Filan Peter M,
McDougall Peter N,
Shekerdemian Lara S
Publication year - 2006
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2006.00835.x
Subject(s) - medicine , congenital diaphragmatic hernia , sildenafil , pulmonary hypertension , pharmacotherapy , persistent pulmonary hypertension , diaphragmatic hernia , prostaglandin e1 , diaphragmatic breathing , enteral administration , cardiology , surgery , hernia , pregnancy , parenteral nutrition , fetus , genetics , alternative medicine , pathology , biology
Pulmonary hypertension can complicate the early clinical course in newborn infants with congenital diaphragmatic hernia. We report the successful use of combination therapy with enteral sildenafil and intravenous prostaglandin E1 in a preterm infant with severe pulmonary hypertension and right heart failure early after congenital diaphragmatic hernia repair.