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Cerebral thrombosis in childhood nephrosis
Author(s) -
Gangakhedkar Arun,
Wong William,
Pitcher Lydia A
Publication year - 2005
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2005.00592.x
Subject(s) - medicine , complication , nephrotic syndrome , nephrosis , thrombosis , pediatrics , heparin , intracranial thrombosis , antithrombin , surgery , venous thrombosis , intensive care medicine
Sinovenous thrombosis is an uncommon but serious complication associated with nephrotic syndrome in children. We describe a 9‐year‐old Caucasian boy who presented with dehydration, vague neurological symptoms and seizures. A diagnosis of nephrotic syndrome was made during the course of hospitalization. The serum antithrombin III level was decreased and brain imaging showed cerebral sinovenous thrombosis. Anticoagulant therapy with heparin was commenced and the patient made a slow but gradual clinical, as well as radiological recovery. We describe this case and review available literature to highlight the importance of suspecting and recognizing this potentially life threatening complication and initiating early treatment.