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Clinical significance of isolated paraventricular cysts on cranial ultrasonography
Author(s) -
Wong F,
Fraser S,
Kelly E,
Acton C
Publication year - 2004
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2004.00462.x
Subject(s) - medicine , clinical significance , gestational age , etiology , ultrasonography , statistical significance , prospective cohort study , cohort study , pediatrics , cohort , gestation , pregnancy , radiology , surgery , genetics , biology
Objectives: Isolated paraventricular cysts detected on routine cranial ultrasonography in premature and full term neonates are often incidental findings. The aetiology and clinical significance of these lesions is uncertain. A case control study was designed to attempt to clarify the clinical significance of isolated paraventricular cysts in terms of growth and neurodevelopment. Methods: Ten infants with isolated paraventricular cysts on neonatal cranial ultrasonography were identified. These were matched with 10 control infants for sex, gestational age and birthweight. All infants were assessed at a corrected age of 18−31 months for growth and neurodevelopment. Two index infants and their controls were excluded from analysis of psychometric data as the neurodevelopmental assessment tools used were different. Results: There was no statistically significant difference between the index and control groups in terms of growth, motor and psychometric assessment at follow up. Conclusions: The study suggests that isolated paraventricular cysts detected on routine cranial ultrasonography have no prognostic significance. However the study involved a small sample size with limited power of study (power = 0.3). A larger prospective cohort study would help to clarify the clinical significance of this condition.