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Maternal diclofenac sodium ingestion and severe neonatal pulmonary hypertension
Author(s) -
Siu KL,
Lee WH
Publication year - 2004
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2004.00319.x
Subject(s) - medicine , ductus arteriosus , diclofenac sodium , pulmonary hypertension , diclofenac , complication , hypertrophic cardiomyopathy , ingestion , cardiology , pregnancy , anesthesia , pharmacology , biology , genetics
We describe a case of severe pulmonary hypertension and transient right‐sided hypertrophic cardiomyopathy in a neonate, caused by premature closure of ductus arteriosus after short‐term maternal use of diclofenac sodium (Voltaren). In view of this associated complication, diclofenac sodium should be avoided during pregnancy. In addition, maternal diclofenac sodium ingestion should be suspected if a newborn develops severe pulmonary hypertension and/or right‐sided hypertrophic cardiomyoptathy with closed ductus arteriosus.