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Lack of plasma leptin response to feeding in newborn infants
Author(s) -
Shimizu T,
Satoh Y,
Shoji H,
Hisata K,
Tadokoro R,
Shinohara K,
Shiga S,
Yamashiro Y
Publication year - 2004
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2004.00288.x
Subject(s) - postprandial , leptin , medicine , breast feeding , endocrinology , plasma levels , plasma concentration , physiology , obesity , pediatrics , insulin
Objective:  Previous reports of the postprandial regulation of leptin are controversial, and there have been few studies on the effects of breast‐feeding on postprandial regulation in newborn infants. We examined the response of plasma leptin to breast‐ and formula‐feeding in newborn infants. Methods:  We measured the plasma leptin levels using an enzyme‐linked immunosorbent assay kit before and after feeding in 12 breast‐fed and 11 formula‐fed mature infants. Results:  There was no significant difference in plasma leptin levels in breast‐fed infants before and after feeding or in artificially fed infants before and after feeding. Conclusion:  Our results suggest that feeding does not play a role in the acute response of circulating leptin levels in either breast‐ or formula‐fed infants.

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