Premium
Neonatal systemic candidiasis
Author(s) -
McDONNELL M,
ISAACS D
Publication year - 1995
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1995.tb00868.x
Subject(s) - medicine , systemic candidiasis , sepsis , intensive care medicine , systemic antibiotics , parenteral nutrition , invasive candidiasis , antibiotics , antifungal , neonatal sepsis , pediatrics , systemic therapy , immunology , dermatology , cancer , fluconazole , corpus albicans , microbiology and biotechnology , biology , breast cancer
: Systemic candidiasis is notoriously difficult to diagnose in neonates; however, it is frequently described and has a high mortality and morbidity. It is particularly likely to occur in extremely low birthweight babies, especially those receiving long‐term parenteral nutrition and antibiotics. The clinical features are non‐specific. Thrombocytopenia occurs in almost all cases of systemic candidiasis, but also in about half the cases of bacterial sepsis. Empirical antifungal therapy should be considered more readily for high‐risk, clinically septic, thrombocytopenic babies.