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Congenital Candida pneumonia in a preterm infant
Author(s) -
NG P. C.,
SIU Y. K.,
LEWINDON P. J.,
WONG W.,
CHEUNG K. L.,
DAWKINS R.
Publication year - 1994
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1994.tb00734.x
Subject(s) - medicine , fluconazole , chorioamnionitis , pneumonia , gestation , pregnancy , dexamethasone , antifungal , pediatrics , intensive care medicine , dermatology , biology , genetics
A 24 week gestation survivor of congenital Candida pneumonia who received prompt antifungal treatment and modern neonatal intensive care is reported. It was an unusual case in that fungal chorioamnionitis occurred without a foreign body in the maternal genital tract. Early diagnosis and treatment of congenital fungal pneumonia was possible because of prior knowledge of the obstetric history. Amphotericin B was successfully used for the treatment of this condition but combination with fluconazole (a fungistatic agent) was unsatisfactory and may be undesirable. Dexamethasone therapy to assist extubation was instituted once the fungal infection had been successfully controlled.