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Breast feeding in neonatal alloimmune thrombocytopenia
Author(s) -
REESE J.,
RAGHUVEER T. S.,
DENNINGTON P. M.,
BARFIELD C. P.
Publication year - 1994
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1994.tb00700.x
Subject(s) - medicine , neonatal alloimmune thrombocytopenia , breast milk , breast feeding , antibody , platelet , immunology , antigen , pregnancy , fetus , immunoglobulin g , obstetrics , pediatrics , biochemistry , genetics , chemistry , biology
Infants with neonatal alloimmune thrombocytopenia are at risk of severe intracranial haemorrhage. Placental transfer of maternal immunoglobulin G (IgG) directed against fetal platelet antigens is known to be the underlying mechanism. Since breast milk contains IgG it is theoretically possible that breast feeding of these infants could cause thrombocytopenia. The following case report shows that an infant with neonatal alloimmune thrombocytopenia may be safely breast fed, even when the breast milk contains the platelet specific antibody (HPA‐1a).