Premium
Coagulopathy with piperacillin administration in cystic fibrosis: Two case reports
Author(s) -
RYE P. J.,
ROBERTS G.,
STAUGAS R. E. M.,
MARTIN A. J.
Publication year - 1994
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1994.tb00635.x
Subject(s) - medicine , coagulopathy , cystic fibrosis , piperacillin , pseudomonas aeruginosa , bacteria , biology , genetics
Two cases are reported of coagulopathy in association with the administration of piperacillin to patients with cystic fibrosis. In both cases the coagulopathy was associated with the development of a serum sickness‐like illness with fever, rash and abnormal liver function tests occurring on day 12 and day 16 of treatment, respectively. On withdrawal of the piperacillin, both the serum sickness and the coagulopathy resolved rapidly, without sequelae.