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An outbreak of Pneumocystis carinii pneumonia in children with malignancy
Author(s) -
CHEUNG Y. F.,
CHAN C. F.,
LEE C. W.,
LAU Y. L.
Publication year - 1994
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1994.tb00605.x
Subject(s) - pneumocystis carinii , medicine , outbreak , pneumonia , malignancy , pneumocystis pneumonia , virology , pathology , pneumocystis jirovecii
An outbreak of Pneumocystis carinii pneumonia (PCP) in three patients within a 6 week period was reported. Two patients had acute lymphoblastic leukaemia and one had brain‐stem glioma. They shared common features of immuno‐suppression and absence of cotrimoxazole prophylaxis and had been nursed in the same room. The severity of PCP and its response to treatment may be related to the degree of immunosuppression. Because of the morbidity and mortality of PCP, chemoprophylaxis should be given to all at‐risk cases. Furthermore, isolation of patients with PCP should be considered in view of increasing evidence of nosocomial transmission.