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Ioxaglate in paediatric angiocardiography
Author(s) -
OGLE G. D.,
SWINBURN M. J.,
McCREDIE R. M.
Publication year - 1991
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1991.tb02538.x
Subject(s) - medicine , angiocardiography , radiology
It is generally agreed that low osmolar contrast media are better tolerated than conventional media. This study examined both tolerance and image quality of ioxaglate in a group of paediatric patients undergoing angiocardiography for congenital heart disease. A consecutive series of 50 patients (mean age 5.47 years; range 4 days‐14 years) were examined. The mean dose of ioxaglate administered per patient was 2.93 mL/kg. In general, ioxoglate was well tolerated. Three patients became febrile and another developed eosinophilia. Serum creatinine rose by a mean of 10 μmol/L. Significant renal dysfunction occurred in 12 patients with an increase in creatinine of 20–30 μmol/L. In no patient, however, were these effects a significant clinical problem. Diagnostic image quality was generally considered to be good with both cine‐angiography and digital subtraction angiographic techniques.