Premium
Peptic ulceration in leukaemia
Author(s) -
SCOTT B.,
HUTSON J. M.
Publication year - 1987
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1987.tb02189.x
Subject(s) - medicine , immunosuppression , cimetidine , surgery , gastroenterology
Two children with leukaemia are described who successfully underwent oversewing of perforated duodenal ulcers which probably were secondary to immunosuppression and steroid therapy. This is only the second report of ulceration in childhood leukaemia. Stress ulceration in children responds favourably to conservative surgery and removal of the insult. Ulcer prophylaxis with antacids or Cimetidine Should be initiated in patients being subjected to combined immunosuppression and high‐dose steroids, particularly during bone marrow transplantation.