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Intracranial embryonal carcinoma and precocious puberty
Author(s) -
CHEUNG P. T.,
LOW L. C. K.
Publication year - 1987
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1987.tb00246.x
Subject(s) - medicine , precocious puberty , embryonal carcinoma , lesion , central precocious puberty , cerebrospinal fluid , pathology , carcinoma , radiology , pediatrics , hormone , biochemistry , chemistry , cellular differentiation , gene
A boy aged 7.5 years presented with precocious onset of secondary sexual characteristics and symptoms and signs of neurological dysfunction. A CT brain scan demonstrated a suprasellar mass lesion. The elevated β‐hCG and α‐fetoprotein concentrations in cerebrospinal fluid and in serum were consistent with a diagnosis of intracranial embryonal carcinoma, although histological diagnosis was not available. The tumour markers β‐hCG and α‐FP should be looked for in all children with precocious puberty presenting with midline brain tumours.