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Effect of ipratropium bromide on respiratory mechanics in infants with acute bronchiolitis
Author(s) -
SEIDENBERG J.,
MASTERS I. B.,
HUDSON I.,
OLINSKY A.,
PHELAN P. D.
Publication year - 1987
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1987.tb00238.x
Subject(s) - ipratropium bromide , medicine , functional residual capacity , bronchiolitis , plethysmograph , respiratory system , anesthesia , respiratory physiology , lung volumes , asthma , lung , bronchodilator
The effect of nebulized ipratropium bromide in 14 infants (mean age:20 weeks, range:4–41) with acute respiratory syncytial virus bronchiolitis was examined. A modified rapid chest compression technique was used to obtain partial expiratory flow‐volume curves and maximum flow at functional residual capacity. Passive respiratory mechanics were assessed by brief occlusion at end inspiration. Thoracic gas volume was measured in a body plethysmograph. No significant difference was found in forced and passive respiratory mechanics pre‐ and post‐ipratropium bromide. No subgroups could be identified. These results do not support the use of ipratropium bromide in acute viral bronchiolitis.