Premium
Complement C8 deficiency with recurrent meningococcemia: Examination of meningococcal opsonization
Author(s) -
KEMP A. S.,
VER JENNIFER,
MULLEREBERHARD H. J.,
BAU D. C. K.
Publication year - 1985
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1985.tb02126.x
Subject(s) - medicine , antibody opsonization , meningococcal infections , meningococcal disease , complement (music) , neisseria meningitidis , microbiology and biotechnology , immunology , antibody , bacteria , opsonin , genetics , biology , phenotype , complementation , gene
A 10 year old girl presented with recurrent febrile episodes over 2 months. A non‐typable strain of Neisseria meningitidis was grown from blood cultures on three occasions. She was found to lack functional C8 activity in serum but material with C8 antigenic activity was present. The opsonic activity of the C8 deficient serum for N. meningidis was equivalent to that of normal controls.