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The diagnosis of periventricular leukomalacia
Author(s) -
LEVENE M. I.
Publication year - 1985
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1985.tb00158.x
Subject(s) - medicine , periventricular leukomalacia , circulatory system , brain damage , fetus , ischemia , cerebral circulation , cerebral perfusion pressure , pregnancy , fetal circulation , gestational age , pediatrics , anesthesia , cardiology , perfusion , genetics , placenta , biology
During the last trimester of pregnancy the perinatal brain undergoes rapid growth and development and premature delivery exposes the brain to complications of circulatory instability including haemorrhage and ischaemia. The type of cerebral injury sustained depends on gestational age, the nature of the insult and the timing of the event. Although compromise of the cerebral circulation is more likely to occur in the infant born premature, the fetus is also dependent on adequate cerebral perfusion and should this fail the unborn infant is liable to similar neuropathological damage as his prematurely born peer.