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Cystic fibrosis heterozygotes have normal autonomic innervation of the heart
Author(s) -
MITCHELL E. A.,
PATEL H.,
WEALTHALL S.R.
Publication year - 1985
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1985.tb00143.x
Subject(s) - heterozygote advantage , cystic fibrosis , medicine , obligate , autonomic nerve , autonomic function , autonomic nervous system , fibrosis , cardiology , endocrinology , pathology , heart rate , allele , genetics , heart rate variability , gene , biology , blood pressure , ecology
Five simple tests of autonomic nerve function based on measurements of cardiovascular responses to various stimuli were used to investigate possible autonomic dysfunction in obligate heterozygotes for cystic fibrosis. There were no significant differences between the heterozygotes and control groups in any of the tests, suggesting that cystic fibrosis heterozygotes have normal autonomic innervation of the heart.