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Perinatal factors, periventricular haemorrhage and mortality in very low birthweight infants
Author(s) -
MURTON L. J.,
BUTT W. W.,
MACKAY R. J.,
ROY R. N. D.,
CRESPIGNY L. Ch.
Publication year - 1985
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1985.tb00121.x
Subject(s) - medicine , intubation , vaginal delivery , endotracheal intubation , perinatal mortality , population , pediatrics , obstetrics , gestation , pregnancy , anesthesia , fetus , environmental health , biology , genetics
In a population of 225 very low birthweight infants born over a 21 month period the cerebroventricular system was scanned by ultrasound. One third of the infants developed a periventricular haemorrhage; in 41% of infants the haemorrhage was detected before an hour of age and 66% of all haemorrhages occurred within the first 24 hours. Statistically significant associations with periventricular haemorrhage included vaginal delivery, endotracheal intubation and intravenous sodium bicarbonate when this was administered in the first 24 hours. In a stepwise regression analysis, however, these and other potentially significant variables added little to the total accountable variance. A similar analysis of perinatal factors and mortality revealed that decreasing gestation was the major association with death.