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Comparison of salbutamol powder with terbutaline aerosol administered with a tube spacer in asthmatic children
Author(s) -
FRANCIS PAUL W. J.,
KELLY CATHERINE A.,
ZIMMERMAN PAUL V.
Publication year - 1983
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1983.tb02112.x
Subject(s) - bronchodilatation , salbutamol , terbutaline , medicine , bronchodilator , anesthesia , asthma
. The bronchodilator effect of 400 μ of salbutamol powder (2 capsules) administered by a rota‐haler was compared with that of 500 μg of terbutaline (2 mete red doses) administered as an aerosol via a tube‐spacer in a group of ten stable asthmatic children (mean age 12 years). The salbutamol powder produced significantly greater bronchodilatation compared with the terbutaline. Forty‐five minutes after the administration of each preparation, nebulised salbutamol was given to determine if further bronchodilatation was possible. Additional bronchodilatation was seen in both groups, the greater additional change being after terbutaline. It is concluded that 400 μg of salbutamol powder was more effective than 500 μg of terbutaline via tube‐spacer but following both preparations, nebulised salbutamol produced significant additional bronchodilatation.