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Hypoxaemia during mechanical ventilation for severe hyaline membrane disease following sedation with morphine sulphate
Author(s) -
BARR PETER A.
Publication year - 1981
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1981.tb01964.x
Subject(s) - medicine , hypoventilation , anesthesia , hyaline , sedation , (+) naloxone , morphine , mechanical ventilation , ventilation (architecture) , hypoxemia , respiratory distress , shunting , respiratory system , surgery , opioid , pathology , mechanical engineering , receptor , engineering
. Severe hypoxaemia following sedation with morphine sulphate is reported during mechanical ventilation in an infant with severe hyaline membrane disease. The hypoxaemia was rapidly reversed with naloxone hydrochloride and was attributed to right‐to‐left shunting presumed secondary to pulmonary hypertension and not to alveolar hypoventilation or ventilation‐perfusion imbalance.