Premium
Parenteral nutrition in infants
Author(s) -
KOO WINSTON W. K.,
FONG THOMAS,
GUPTA JAGDISH M.
Publication year - 1980
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1980.tb01288.x
Subject(s) - medicine , parenteral nutrition , catheter , extravasation , surgery , vein , regimen , sepsis , complication , prospective cohort study , pathology
A prospective study of 63 consecutive infants on parenteral nutrition was undertaken to evaluate the effectiveness of a uniform regimen with minor modifications throughout the project. Routine investigations were carried out to monitor haematological and metabolic complications. Anaemia from repeated blood sampling was frequent. Metabolic complications were infrequent and were usually transitory. Parenteral nutrition per se did not appear to be a cause of jaundice, though histological changes in the liver were found in 12 of the 17 patiènts studied. Lipid profile showed disturbances which appeared to be dose related. Catheter related complications were frequent and occurred irrespective whether the catheter was inserted by the cutdown method or percutaneously. Tissue necrosis and ulceration due to extravasation of parenteral nutrition fluid and localised abscesses were the complications encountered with peripheral vein infusion. The study shows that it is possible to use a simple set of solutions for parenteral nutrition. It also emphasises that routine monitoring is necessary to detect the metabolic disturbances early and catheter related complications can be reduced by careful attention to technique.