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Infantile xanthomatous cardiomyopathy
Author(s) -
RADFORD DOROTHY J.,
CHALK SANDRA M.
Publication year - 1980
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1980.tb01278.x
Subject(s) - medicine , cardiomyopathy , autopsy , cardiology , ventricular fibrillation , white (mutation) , heart failure , biochemistry , chemistry , gene
A 10‐month‐old female infant with Wolff‐Parkinson‐White syndrome and atrlal and ventricular tachyarrhythmias is described. She developed atrial fibrillation with a ventricular rate of 400 per minute. With antiarrhythmic drug therapy she survived 9 months. Autopsy showed typical features of infantile xanthomatous cardiomyopathy with vacuolated fatty cells replacing the normal myofibres. The Wolff‐Parkinson‐White syndrome has occurred in other cases of this rare cardiomyopathy which has a marked female predominance and occurs In children under the age of 2 years.