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Rapid Diagnosis of Rotavirus Infection: Comparison of Electron Microscopy and Enzyme Linked Immunosorbent Assay (Elisa)
Author(s) -
ROBERTON D. M.,
HARRISON M.,
HOSKING C. S.,
ADAMS L. C.,
BISHOP R. F.
Publication year - 1979
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1979.tb01235.x
Subject(s) - rotavirus , electron microscope , medicine , microscopy , virology , enzyme , antigen , immunology , virus , pathology , biology , biochemistry , optics , physics
Roberton, D. M., Harrison, M., Hosking, C.S., Adams, L. C. and Bishop, R. F. (1979).Aust. Paediatr. J. , 15, 229–232. Rapid diaggnosis of rotavirus infection: Comparison of electron microscopy and enzyme linked immunosorbent assay (ELISA). Commonly used methods for detecting rotavirus antigen in stool are either relatively insensitive (counter‐immuno‐electrophorosis) or suitable only for research laboratories (electron microscopy). In this paper we describe an enzyme linked immunosorbent assay that compares favourably with electron microscopy in terms of sensitivity and is adaptable for use in hospitals or for epidemiological studies in the field.