Premium
Antibody Responses to Influenza Virus Vaccine in Patients With Acute Lymphocytic Leukaemia
Author(s) -
FEERY B. J.,
MATTHEWS R. N.,
EVERED M. G.,
GALLICHIO H. A.
Publication year - 1979
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1979.tb01220.x
Subject(s) - medicine , antibody , immunology , immunization , antibody response , virus , antigen , acute lymphocytic leukemia , influenza vaccine , virology , leukemia , lymphoblastic leukemia
Feery, B. J., Matthews, R. N., Evered, M. G., and Gallichio, H. A. (1979).Aust. Paediatr. J. , 15, 177–180. Antibody responses to influenza virus vaccine in children with acute lymphocytic leukaemia. Antibody responses to influenza immunization in children with acute lymphocytic leukaemia in remission were studied in two successive years. Initial antibody levels, the response to immunization, and final antibody levels were lower than in a group of children with cystic fibrosis. The results indicate that both primary and anamnestic antibody responses are depressed in children with acute leukaemia when they are on immunosuppressive therapy. Despite this depression the majority of the patients reached protective antibody levels to the A/Victoria/3/75 and A/Texas/1/77 (H3N2) antigens but not to the recent A/USSR/90/77 (H1N1) antigens.