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Red Cell Superoxide Dismutase Activity in the Newborn
Author(s) -
LEGGE MICHAEL,
BRIAN MAUREEN,
WINTERBOURN CHRISTINE,
CARRELL ROBIN
Publication year - 1977
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1977.tb01892.x
Subject(s) - medicine , superoxide dismutase , respiratory distress , cord blood , andrology , red blood cell , physiology , endocrinology , oxidative stress , anesthesia
Red cell superoxide dismutase activity was determined on cord blood samples. The normal range of activity in neonates, measured per gram of haemoglobin, was lower than that obtained for adults, with the mean value for neonates being approximately two‐thirds of the adult level. When activity was measured on a per cell basis it was still lower than the adult level. Adult levels are reached at approximately three months postnatal age. No correlation was found between low superoxide dismutase activity and prematurity, low birthweight. Apgar, respiratory distress syndrome, or sex.