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Ventilatory Disturbance in Children with Obstructive Lung Disease
Author(s) -
MELLIS CRAIG M.,
LANDAU LOUIS I.
Publication year - 1976
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1976.tb02340.x
Subject(s) - medicine , cystic fibrosis , nitrogen washout , lung , lung function , washout , asthma , disturbance (geology) , obstructive lung disease , lung disease , disease , respiratory disease , cardiology , gastroenterology , pulmonary disease , lung volumes , functional residual capacity , paleontology , biology
Mellis, C. M. and Landau, L. I. (1976).Aust. paediat. J. , 12, 77–82. Ventilatory disturbance in children with obstructive lung disease. Disease in the small airways leads to alteration in the slope of phase III of the single breath nitrogen washout following a breath of 100% oxygen. Normal children and those with asthma and cystic fibrosis were studied by this technique. Measurement of the slope of phase III of the single breath washout appeared to be a sensitive indicator of abnormal pulmonary function in children with these diseases. Results obtained in many children with cystic fibrosis suggested that the upper lung regions were predominantly affected.