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Migration inhibitory factor production by lymphoid cells of Australian Aboriginal children with moderate protein‐calorie malnutrition
Author(s) -
FORD G.W.,
JAKEMAN M.,
JOSE D.G.,
VORBACH E.A.,
KIRKE D.K.
Publication year - 1975
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1975.tb02304.x
Subject(s) - medicine , protein calorie malnutrition , malnutrition , calorie , inhibitory postsynaptic potential , environmental health , immunology , protein–energy malnutrition
Australian Aboriginal children with moderate protein‐calorie malnutrition showed a high incidence of impaired production of migration inhibitory factor (MIF) from blood lymphoid cells on in vitro stimulation with Candida albicans antigen. This impairment persisted with the control of infection and nutritional repletion. MIF production to two other antigens, streptolysin‐O and lymphocyte membrane extract, was normal or increased.