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LUNG DISEASE ASSOCIATED WITH INFANTILE AGAMMAGLOBULINAEMIA
Author(s) -
PHELAN P. D.,
LANDAU L. I.,
WILLIAMS H. E.
Publication year - 1973
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1973.tb01868.x
Subject(s) - medicine , lung , disease , pneumonia , sinusitis , chronic sinusitis , lung disease , otitis , pediatrics , surgery , pathology
SYNOPSIS The clinical features of the pulmonary disease in 8 boys with infantile X‐linked agam‐maglobulinaemia seen at the Royal Children's Hospital between 1958 and 1972 are reviewed. Recurrent pneumonia which was often bilateral, was common. Resolution of these infections was slow and often incomplete in the dependent lobes, and persistent collapse occurred in 7 of the 8 patients. Less efficient clearing of the dependent lobes by cough was the probable cause of the localised distribution of the chronic lung disease. Chronic otitis was common, but chronic sinusitis was not. Regular injections of γ‐globulin did not prevent progressive lung disease.