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CONGENITAL LOBAR EMPHYSEMA ETIOLOGICAL STUDIES
Author(s) -
CAMPBELL P. E.
Publication year - 1969
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1969.tb02754.x
Subject(s) - congenital lobar emphysema , medicine , cartilage , abnormality , microdissection , pathology , etiology , bronchography , anatomy , pulmonary emphysema , radiology , lung , biochemistry , chemistry , psychiatry , gene
SYNOPSIS The cartilage in the bronchi of 12 cases of congenital lobar emphysema has been examined using 3 techniques: a) microdissection, b) serial macroscopic slices and c) serial histological sections. The first technique is considered to be the best for it enables the cartilage content of the entire bronchial tree to be clearly seen, and focal or generalised deficiencies can be identified. In all 12 cases the amount of cartilage in the bronchi was significantly less than in normal controls and it is postulated that this deficiency is the fundamental abnormality in congenital lobar emphysema.