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HISTAMINE BINDING IN SERUM OF CHILDREN WITH ASTHMA
Author(s) -
FREEMAN MAVIS
Publication year - 1969
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.1969.tb02734.x
Subject(s) - medicine , histamine , asthma , gamma globulin , in vitro , immunology , antibody , biochemistry , chemistry
SYNOPSIS Investigations of sera from asthmatic patients have been undertaken in an attempt to discover basic differences from normal sera. Asthmatic sera are predominantly histaminopexy negative, that is, they do not combine with histamine in vitro. The sera of normal children show the opposite effect. The protein fraction responsible for binding histamine, plasmapexin, has been shown to be associated with gamma globulin.