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Efficacy and safety of low‐pressured and short‐time dilation in endoscopic papillary balloon dilation for bile duct stone removal
Author(s) -
Tsujino Takeshi,
Kawabe Takao,
Isayama Hiroyuki,
Sasaki Takashi,
Kogure Hirofumi,
Togawa Osamu,
Arizumi Toshihiko,
Ito Yukiko,
Matsubara Saburo,
Yamamoto Natsuyo,
Nakai Yousuke,
Sasahira Naoki,
Hirano Kenji,
Toda Nobuo,
Komatsu Yutaka,
Tada Minoru,
Yoshida Haruhiko,
Omata Masao
Publication year - 2008
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.2007.05267.x
Subject(s) - medicine , balloon dilation , dilation (metric space) , bile duct , bile duct diseases , balloon , radiology , surgery , general surgery , mathematics , combinatorics
Background and Aim: Endoscopic papillary balloon dilation (EPBD) has been advocated as an alternative therapy to endoscopic sphincterotomy for bile duct stones. However, studies have shown that EPBD may increase the risk for pancreatitis. Pancreatitis after EPBD is believed to be related to papillary damage after balloon dilation. We changed the dilation method to a theoretically less hazardous one. This modified dilation method was compared with the initial method. Methods: A total of 324 patients with bile duct stones underwent EPBD by the modified method between June 1999 and June 2003. Three hundred and twenty‐four patients undergoing EPBD by the initial method served as a historical control group. The success rate of stone removal and the incidence of procedure‐related pancreatitis were compared between the two groups. In the modified method, the balloon was inflated until disappearance of the balloon waist, and the pressure was then maintained for 15 s. In the initial method, the balloon was inflated at 8 atmospheres for 2 min. Results: Bile duct stones were successfully removed in 313 of 324 patients (96.6%) in the modified group and in 314 of 324 patients (96.9%) in the initial group (not significant). The incidence of postprocedure pancreatitis showed a lower tendency in the modified group (4.0%, 13/324) than in the initial group (7.4%, 24/324) ( P ‐value = 0.0626). The severity of pancreatitis was significantly reduced in the modified group. Conclusion: The modified method of EPBD is feasible for extraction of bile duct stones, and may potentially decrease the incidence of severe post‐EPBD pancreatitis.