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Bacterial translocation: Overview of mechanisms and clinical impact
Author(s) -
Balzan Silvio,
De Almeida Quadros Claudio,
De Cleva Roberto,
Zilberstein Bruno,
Cecconello Ivan
Publication year - 2007
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.2007.04933.x
Subject(s) - bacterial translocation , chromosomal translocation , medicine , bacteria , intensive care medicine , bioinformatics , biology , genetics , gene
Bacterial translocation (BT) is a phenomenon in which live bacteria or its products cross the intestinal barrier. Gut translocation of bacteria has been shown in both animal and human studies. BT and its complications have been shown clearly to occur in animal models, but its existence and importance in humans has been difficult to ascertain. We review the mechanisms of BT and its clinical impact based on the current literature.